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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UGDH
All Species:
39.7
Human Site:
T461
Identified Species:
62.38
UniProt:
O60701
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60701
NP_003350.1
494
55024
T461
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Chimpanzee
Pan troglodytes
XP_001142047
469
52425
T436
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001092812
494
55060
T461
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Dog
Lupus familis
XP_536254
494
55056
T461
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Cat
Felis silvestris
Mouse
Mus musculus
O70475
493
54813
T461
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Rat
Rattus norvegicus
O70199
493
54873
T461
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511646
494
54796
T461
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Chicken
Gallus gallus
Q5F3T9
494
55046
T461
V
I
G
F
Q
I
E
T
I
G
K
K
V
S
A
Frog
Xenopus laevis
NP_001079465
494
55258
T461
N
I
G
F
Q
V
E
T
I
G
K
K
V
A
S
Zebra Danio
Brachydanio rerio
NP_001103872
493
54559
T463
N
V
G
F
Q
I
E
T
I
G
K
K
V
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02373
476
52856
D443
F
D
G
R
K
I
L
D
H
E
R
L
Q
Q
I
Honey Bee
Apis mellifera
XP_396801
479
52985
D446
F
D
G
R
K
I
L
D
H
D
K
L
Q
K
I
Nematode Worm
Caenorhab. elegans
Q19905
481
52737
Q452
D
G
R
L
I
L
D
Q
K
A
L
R
E
I
G
Sea Urchin
Strong. purpuratus
XP_784861
476
52439
L447
A
F
D
G
R
R
L
L
D
S
S
L
L
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LIA8
480
53155
M450
V
F
D
G
R
N
I
M
N
L
Q
K
L
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
99.3
99.3
N.A.
97.7
97.5
N.A.
96.9
93.7
88.4
84.4
N.A.
64.9
67
62.3
69
Protein Similarity:
100
94.9
99.3
100
N.A.
99.1
98.7
N.A.
98.5
97.9
94.5
92.3
N.A.
79.7
81.9
75.5
81.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
80
73.3
N.A.
13.3
20
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
26.6
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
74.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
7
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
14
0
0
0
7
14
7
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
67
0
0
7
0
0
7
7
7
% E
% Phe:
14
14
0
67
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
80
14
0
0
0
0
0
67
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% H
% Ile:
0
60
0
0
7
74
7
0
67
0
0
0
0
7
14
% I
% Lys:
0
0
0
0
14
0
0
0
7
0
74
74
0
7
0
% K
% Leu:
0
0
0
7
0
7
20
7
0
7
7
20
14
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% M
% Asn:
14
0
0
0
0
7
0
0
7
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
67
0
0
7
0
0
7
0
14
7
0
% Q
% Arg:
0
0
7
14
14
7
0
0
0
0
7
7
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
7
0
0
54
54
% S
% Thr:
47
0
0
0
0
0
0
67
0
0
0
0
0
0
7
% T
% Val:
14
7
0
0
0
7
0
0
0
0
0
0
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _